My educational interests are microbiology, infectious disease and global rural health.
The focus of our molecular parasitology laboratory is trypanosomes. These vector-borne protozoan parasites cause World Health Organization-designated Neglected Tropical Diseases that are endemic to poor, rural populations and for which new drug targets are urgently needed. The laboratory studies the stability and degradation of RNA, an important control point of trypanosome gene expression as transcription of both mitochondrial and nuclear genomes is constitutive in these organisms.
Zimmer Group News
2016-04-25 Murat Kalem and Dr. Sara Zimmer present talks entitled "Metabolism and the maxicircle genome: exploring potential relationships using Trypanosoma cruzi strain variability" and "Deep analysis of tails on Trypanosoma brucei mitochondrial transcripts reveals life stage as well as transcript-specific regulation" at the Kinetoplastid Molecular Cell Biology VII in Woods Hole, MA.
2016-04-03 Murat Kalem, former undergraduate (Jan 2017) and current technician, accepts his offer of admission to the PhD Program in Biomedical Sciences at University at Buffalo (SUNY) starting Fall 2017.
2016-10-14 The lab's presentation at the Rustbelt RNA Meeting, marks first participation of University of Minnesota researchers in this fantastic meeting.
2016-07-01 The Zimmer laboratory is grateful for an American Heart Association Scientist Development Grant awarded to Dr. Sara Zimmer for Chagas disease research.
2016-06-24 The lab welcomes its second graduate student: Emily Masters, graduate of University of Wisconsin-La Crosse.
2016-06-19 A great time was had by all attendees of TryTax2 in Ostrava, CZ, where one of our projects was presented.
2016-06-06 The lab welcomes its first graduate student: Charlie Liggett, graduate of St. Olaf College, Northfield, MN.
2016-04-23 Murat Kalem presents a talk entitled "Strain specific differences in Typanosoma cruzi culture metacyclogenesis" at the American Society for Microbiology Intermountain Branch Meeting in Salt Lake City, Utah.
2016-04-04 Undergraduate Bailey Rasumussen receives a Summer Undergradate Research Program (SURP) fellowship through the Department of Chemistry and Biochemistry, University of Minnesota Duluth.
2016-02-12 Generous support from Illumina and the University of Minnesota Genomics Center NGS Pilot Project Grant Program allows us to pursue a promising new research direction.
2016-01-30 One of our intriguing trypanosomes is in the National news! National Public Radio reports on the evolution of Trypanosoma brucei gambiense.
2015-09-28 Dr. Aubie Shaw receives International Travel Grant from the Global Programs and Strategy Alliance, University of Minnesota, to cover portions of travel to XXXI Annual Meeting of the Brazilian Society of Protozoology and XLII Annual Meeting on Basic Research in Chagas' Disease. She has been selected to give a talk from among submitted meeting abstracts.
2015-08-25 Rebecca Madden and Murat Kalem have their summer BURST fellowship experience in the Zimmer Lab profiled as a University of Minnesota-Duluth press release. The BURST program was also featured in the Duluth News Tribune.
2015-06-24 Dr. Aubie Shaw is selected as a ParaTryp Research Travel Award Recipient.
2015-04-25 Drs. Aubie Shaw and Sara Zimmer attend Kinetoplastid Molecular Cell Biology VI in Woods Hole, MA, where Aubie gives a talk on her work on T. cruzi mitochondrial gene expression.
2015-01-01 The Zimmer Laboratory is awarded a Whiteside Institute for Clinical Research Grant.